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| Name | Cre lox recombination system |
| Video Uploader | Video From Shomu's Biology |
| Upload Date | This Video Uploaded At 26-01-2013 17:11:39 |
| Video Discription | This recombination lecture explains about cre lox recombination system. http://shomusbiology.com/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page- https://www.facebook.com/ShomusBiology/ Twitter - https://twitter.com/shomusbiology SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/113648584982732129198 LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661 Youtube- https://www.youtube.com/user/TheFunsuman Thank you for watching Cre-Lox recombination is a site-specific recombinase technology widely used to carry out deletions, insertions, translocations and inversions in the DNA of cells. It allows the DNA modification to be targeted to a specific cell type or be triggered by a specific external stimulus. It is implemented both in eukaryotic and prokaryotic systems. The system consists of a single enzyme, Cre recombinase that recombines a pair of short target sequences called the Lox sequences. This system can be implemented without inserting any extra supporting proteins or sequences. The Cre enzyme and the original Lox site called the LoxP sequence are derived from a bacteriophage P1. Placing Lox sequences appropriately will allow genes to be activated, repressed, or exchanged for other genes. At a DNA level many types of manipulations can be carried out. The activity of the Cre enzyme can be controlled so that it is expressed in a particular cell type or triggered by an external stimulus like a chemical signal or a heat shock. These targeted DNA changes are useful in cell lineage tracing and when mutants are lethal if expressed globally. The Cre-Lox system is very similar in action and in usage to the FLP-FRT recombination system.[1] Source of the article published in description is Wikipedia. I am sharing their material. © by original content developers of Wikipedia. Link- http://en.wikipedia.org/wiki/Main_Page Material source: Molecular Biology of the Gene (4th Edition) James D. Watson (Author), Alan M. Weiner (Author), Nancy H. Hopkins (Author) Link: http://www.amazon.com/Molecular-Biology-Gene-4th-Edition/dp/0805396144 [Msyn8MHJ2Fk] |
| Category | Education |
| Tags | biology education | teaching | life sciences | genetics | molecular biology | cell biology | suman bhattacharjee | shomu's biology | zoology | DNA | proteins | cre-lox recombination | cre lox recombination | site specific recombination | cre protein | recombination in bacteriophage | lox sites | dna recombination | cssr | tyrosine recombinase | serine recombinase | Cre Recombinase | Cre lox recombination system | Cre lox recombination | Genetic Recombination (Award-Winning Work) |
