Hello guys, Welcome to Africa's Largest Video Search Engine, and you are watching A B Exotoxins Diphtheria Exotoxin - Microbiology animations. and this video is uploaded by Dr.G Bhanu Prakash Animated Medical Videos at 2019-01-02T22:07:59-08:00. We are just promoting this video only for entertainment and educational purpose only. I hop you like our Video Search Engine. [JTAOQHtClxA]
| Name | A B Exotoxins Diphtheria Exotoxin - Microbiology animations |
| Video Uploader | Video From Dr.G Bhanu Prakash Animated Medical Videos |
| Upload Date | This Video Uploaded At 03-01-2019 06:07:59 |
| Video Discription | 📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- https://www.instagram.com/drgbhanuprakash 📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash The AB toxins are two-component protein complexes secreted by a number of pathogenic bacteria. They can be classified as Type III toxins because they interfere with internal cell function. They are named AB toxins due to their components: the "A" component is usually the "active" portion, and the "B" component is usually the "binding" portion. The "A" subunit possesses enzyme activity, and is transferred to the host cell following a conformational change in the membrane-bound transport "B" subunit. Among the toxins produced by certain Clostridium spp. are the binary exotoxins. These proteins consist of two independent polypeptides, which correspond to the A/B subunit moieties. The enzyme component (A) enters the cell through endosomes produced by the oligomeric binding/translocation protein (B), and prevents actin polymerisation through ADP-ribosylation of monomeric G-actin. Examples of the "A" component of an AB toxin include C. perfringens iota toxin Ia, C. botulinum C2 toxin CI, and Clostridium difficile ADP-ribosyltransferase .Other homologous proteins have been found in Clostridium spiroforme. An example of the B component of an AB toxin is Bacillus anthracis protective antigen (PA) protein,B. anthracis secretes three toxin factors: the protective antigen (PA); the oedema factor (EF); and the lethal factor (LF). Each is a thermolabile protein of ~80kDa. PA forms the "B" part of the exotoxin and allows passage of the "A" moiety (consisting of EF or LF) into target cells. PA protein forms the central part of the complete anthrax toxin, and translocates the A moiety into host cells after assembling as a heptamer in the membrane. The Diphtheria toxin also is an AB toxin. It inhibits protein synthesis in the host cell through phosphorylation of the eukaryotic elongation factor 2, which is an essential component for protein synthesis. The exotoxin A of Pseudomonas aeruginosa is another example of an AB toxin that targets the eukaryotic elongation factor 2. The AB5 toxins are usually considered a type of AB toxin, characterized by B pentamers. Less commonly, the term "AB toxin" is used to emphasize the monomeric character of the B component. #abexotoxins #exotoxins #diphtheriatoxin #usmleanimations #mbbsanimations #medicalanimations #microbiologyanimations [JTAOQHtClxA] |
| Category | Education |
| Tags | usmle videos | medicine | usmle | usmle step 2 | The AB toxins | AB toxins | bacterial exotoxin | diptheria exotoxin | diptheria | exotoxins | animated microbiology | microbiology animations | animations in microbiology | medical microbiology animations | usmle step 1 | uworld | ab toxins | ab toxins animation | diphtheria toxin mechanism of action | diptheria toxin animation | diphtheria toxin | AB Toxin microbiology | mbbs animations | usmle animations | exotoxin animation |
