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| Name | Junk DNA... It's a Thing |
| Video Uploader | Video From Zach B. Hancock |
| Upload Date | This Video Uploaded At 09-07-2024 00:30:06 |
| Video Discription | The concept of junk DNA - the notion that some portion of the genomes of every organism is non-functional - has been around for over 60 years. And yet, many people, including some biologists, don't seem to understand it. In this video, I review the history of the concept, including framing junk DNA in an ecological and population genetic lens, demonstrating that it's virtually guaranteed to exist. We also take a deep dive into the infamous ENCODE controversy, discussing notions of biological function, and the many methodological, statistical, and conceptual errors of the consortium. https://youtu.be/MUohUfW4U04 #junkdna #evolution #education Links to @CreationMyths ongoing feud with the Discovery Institute over junk DNA: https://youtu.be/HB6Ilu5zo4U?si=J_kFMEpO1Z8-ryWR https://www.youtube.com/playlist?list=PLzz-uby_-OesLnhYK4oYuf1JGrnmJQuLD https://evolutionnews.org/2024/05/reflections-on-casey-luskins-debate-with-dr-dan/ https://evolutionnews.org/2024/05/did-dr-dan-make-us-change-our-position-on-junk-dna/ https://evolutionnews.org/2024/06/dr-dan-has-a-taste-for-debate/ https://evolutionnews.org/2024/06/documentation-for-dr-dan/ References and further reading: Graur, D., Zheng, Y., Price, N., Azevedo, R. B., Zufall, R. A., & Elhaik, E. (2013). On the immortality of television sets: “function” in the human genome according to the evolution-free gospel of ENCODE. Genome biology and evolution, 5(3), 578-590. (https://academic.oup.com/gbe/article/5/3/578/583411) Palazzo, A. F., & Gregory, T. R. (2014). The case for junk DNA. PLoS genetics, 10(5), e1004351. (https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004351) Doolittle, W. F. (2013). Is junk DNA bunk? A critique of ENCODE. Proceedings of the National Academy of Sciences, 110(14), 5294-5300. (https://www.pnas.org/doi/abs/10.1073/pnas.1221376110) Kellis, M., Wold, B., Snyder, M. P., Bernstein, B. E., Kundaje, A., Marinov, G. K., ... & Hardison, R. C. (2014). Defining functional DNA elements in the human genome. Proceedings of the National Academy of Sciences, 111(17), 6131-6138. (https://www.pnas.org/doi/abs/10.1073/pnas.1318948111) Lynch, M., & Marinov, G. K. (2015). The bioenergetic costs of a gene. Proceedings of the National Academy of Sciences, 112(51), 15690-15695. (https://www.pnas.org/doi/abs/10.1073/pnas.1514974112) Lynch, M., & Conery, J. S. (2003). The origins of genome complexity. science, 302(5649), 1401-1404. (https://doi.org/10.1126/science.1089370) Ohno, S (1972). So much "junk" DNA in our genome. Brookhaven Symposia in Biology. 23: 366–70. Moran, L. A. (2023). What's in Your Genome?: 90% of Your Genome Is Junk. University of Toronto Press. [0SEKs4bAlHM] |
| Category | Science & Technology |
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