Hello guys, Welcome to Africa's Largest Video Search Engine, and you are watching Antibody Humanization | Humanized Antibody | Recombinant Antibody |. and this video is uploaded by BMH learning at 2022-05-02T06:18:52-07:00. We are just promoting this video only for entertainment and educational purpose only. I hop you like our Video Search Engine. [iN64QE_3s6c]
| Name | Antibody Humanization | Humanized Antibody | Recombinant Antibody | |
| Video Uploader | Video From BMH learning |
| Upload Date | This Video Uploaded At 02-05-2022 13:18:52 |
| Video Discription | In an attempt to reduce the immunogenicity of the mouse antibodies, genetic engineering is used to generate chimeric antibodies containing human constant domains and the mouse variable domains to retain the specificity Humanization is important.... To reduce the immunogenicity of monoclonal antibodies derived from xenogeneic sources (commonly rodents .... to improve their activation of the human immune system Rodent antibodies .... are highly immunogenic in humans, which limits their clinical applications, toxicity due to cross-reaction with proteins in the body Importantly, they are rapidly removed from circulation ....and can cause systemic inflammatory effects as well. [iN64QE_3s6c] |
| Category | Education |
| Tags | antibody | human antibody | antibody engineering | monoclonal antibody | humanized antibody | antibody humanization | antibodies | cdr grafting | chain shuffling | light chain | heavy chain Creative Biolabs | CAMouse™ | Human Antibody | Transgenetic Mouse | Antibody Discovery | VHH Strain | VHL Strain | VHK Strain |
