Hello guys, Welcome to Africa's Largest Video Search Engine, and you are watching The Renin–Angiotensin–Aldosterone System, RAAS, Animation. and this video is uploaded by Alila Medical Media at 2020-09-29T10:00:51-07:00. We are just promoting this video only for entertainment and educational purpose only. I hop you like our Video Search Engine. [6EUSEa6Lw8g]
| Name | The Renin–Angiotensin–Aldosterone System, RAAS, Animation |
| Video Uploader | Video From Alila Medical Media |
| Upload Date | This Video Uploaded At 29-09-2020 17:00:51 |
| Video Discription | (USMLE topics) Renal control of blood pressure via RAAS. Purchase a license to download a non-watermarked version of this video on AlilaMedicalMedia(dot)com Check out our new Alila Academy - AlilaAcademy(dot)com - complete video courses with quizzes, PDFs, and downloadable images. Voice by: Ashley Fleming ©Alila Medical Media. All rights reserved. All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. The renin–angiotensin–aldosterone system, RAAS, is a hormonal system that controls blood pressure. While baroreflex is a short-term response to sudden changes in blood pressure, RAAS is responsible for long-term regulation. In the kidneys, within the walls of afferent arterioles, there are specialized cells producing prorenin called juxtaglomerular cells. Upon activation by a drop in blood pressure, prorenin is cleaved to form renin, which is released into the blood. Renin converts a plasma protein called angiotensinogen, produced by the liver, into angiotensin I, a peptide of 10 amino acids. Angiotensin I is further converted into angiotensin II, an 8-amino acid peptide, by the angiotensin-converting enzyme, ACE, predominantly present in the lungs and kidneys. Angiotensin II is a hormone. It binds to angiotensin II receptors in tissues to exert various effects: - It promotes sodium reabsorption in proximal convoluted tubules of the kidneys. - It stimulates vasoconstriction in systemic arterioles. - It induces the release of aldosterone from the adrenal cortex. Aldosterone promotes sodium and water retention in the kidneys. - In the central nervous system, angiotensin II has several effects: + It acts on the hypothalamus to stimulate thirst and encourage water intake. + It induces the posterior pituitary to release antidiuretic hormone, which promotes water retention by the kidneys. + It reduces the sensitivity of the baroreceptor response to increased blood pressure, so that this response would not counteract the effect of RAAS. All these actions lead to an increase in blood volume and blood pressure. Angiotensin II is short-lived with a half-life of 1 to 2 minutes. It is degraded into angiotensin III and IV, which have lesser effects. Overactive or inappropriately activated RAAS is a cause for hypertension. RAAS is a frequent target of anti-hypertensive drugs. ACE inhibitors and angiotensin receptor blockers are common treatment for hypertension. [6EUSEa6Lw8g] |
| Category | Education |
| Tags | renal regulation of blood pressure | RAS | blood pressure | kidneys | prorenin | angiotensinogen | angiotensin I | angiotensin II | ACE | hormone | angiotensin II receptors | effects | vasoconstriction | release of aldosterone | functions of angiotensin 2 | CNS | ADH | vasopressin | baroreceptor response | mechanisms of action | hypertension | animated | artery | cardiology | cardiovascular | high blood pressure | medical | medicine | mode of action | nephrons | vasoactive | vasomotor tone | nephrology | lecture | USMLE | NCLEX |
